MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA type c) is a mitochondria derived peptide encoded within the mitochondrial genome rather than the nuclear genome. A discovery that fundamentally expanded the understood coding capacity of the mitochondrial genome beyond oxidative phosphorylation machinery. Hudson Science’s 10mg lyophilized vial delivers the lowest concentration standalone MOTS-C presentation in CSD’s range. Below the iLab Pharma 40mg lyophilized vial and F40 Biotech 60mg prefilled pen, providing the most accessible entry point into MOTS-C research and the most granular low dose titration capability for researchers establishing initial dose response characterization at conservative concentration points. MOTS-C’s primary research mechanism centres on AMPK pathway activation through mitochondria to nucleus translocation in response to metabolic stress. A retrograde signaling pathway that directly influences nuclear gene expression and represents a novel mechanism of metabolic regulation not previously attributed to mitochondrially encoded peptides. AMPK activation downstream of MOTS-C signaling promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis while suppressing energy consuming anabolic pathways. Coordinated metabolic response generating significant research interest across insulin sensitivity, exercise mimetics, obesity, and age related metabolic decline studies. MOTS-C’s well documented plasma concentration decline with age additionally positions it as a key subject in mitochondrial peptide mediated ageing research alongside Epithalon and NAD in CSD’s longevity compound range. CSD stocks MOTS-C across three formats: this Hudson Science 10mg lyophilized vial, the iLab Pharma 40mg lyophilized vial, and the F40 Biotech 60mg prefilled pen, alongside its inclusion as a component in the iLab Pharma Anti Aging Peptide Stack. The 10mg single vial serves as the protocol entry point and dose response lower reference, the 40mg vial suits extended standalone protocols requiring reconstitution flexibility, and the 60mg pen provides ready to use administration convenience for repeated parenteral research schedules. Giving researchers complete MOTS-C format and concentration flexibility from a single verified Canadian supplier. Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s MOTS-C meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior. Reconstitute with bacteriostatic water prior to use. Store lyophilized peptide at 2–8°C away from direct light. Once reconstituted refrigerate and use within 28 days. Intended for research purposes only. Commonly researched alongside Epithalon and NAD in comparative longevity and mitochondrial metabolic regulation studies. Browse CSD’s full peptide range for complete sourcing.